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Key Documents

138R-2

Sigma-Aldrich

CD138 (EP201) Rabbit Monoclonal Primary Antibody

clone EP201, unconjugated, Cell Marque

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About This Item

Kod UNSPSC:
12352203
NACRES:
NA.41

pochodzenie biologiczne

rabbit

Poziom jakości

100
500

białko sprzężone

unconjugated

forma przeciwciała

culture supernatant

rodzaj przeciwciała

primary antibodies

klon

EP201, monoclonal

opis

(For In Vitro Diagnostic Use in Select Regions (See Chart))

Postać

buffered aqueous solution

reaktywność gatunkowa

human

opakowanie

bottle of 1.0 mL predilute (138R-27)
bottle of 7.0 mL predilute (138R-28)
vial of 0.1 mL concentrate (138R-24)
vial of 0.5 mL concentrate (138R-25)
vial of 1.0 mL concentrate (138R-26)

producent / nazwa handlowa

Cell Marque

metody

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

izotyp

IgG

Warunki transportu

wet ice

temp. przechowywania

2-8°C

informacje o genach

human ... SDC1(6382)

Opis ogólny

CD138, Syndecan 1, is expressed in the late stages of B-cell differentiation with progression towards plasma cells.1,2 It can be used to differentiate lymphoplasmacytic lymphoma from marginal zone lymphoma.1 ALK+ large B-cell lyphoma (LBCL) usually strongly expresses CD138 whereas lineage-associated markers such as anti-CD20 and anti-CD79a do not stain ALK+LBCL.3,7 Anti-CD138 is immunoreactive with HHV8-associated primary effusion lymphoma even though the lymphoma cells lack the expression of B-cell markers.5 Anti-CD138 is a good marker to identify and enumerate plasma cells, benign, reactive, or malignant, in bone marrow biopsy specimens.4,6 CD138 is also expressed in epithelial cells.6

Jakość


IVD

IVD

IVD

RUO

Powiązanie

CD138 Positive Control Slides, Product No. 138S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview.
E Sabattini et al.
Pathologica, 102(3), 83-87 (2010-12-22)
A Sebestyén et al.
British journal of haematology, 104(2), 412-419 (1999-03-02)
Syndecan-1, an important transmembrane heparan sulphate proteoglycan is expressed in distinct stages of differentiation of normal lymphoid cells: in pre-B cells and Ig-producing plasma cells; however, its normal function, or presence in lymphoid malignancies, is still largely unknown. The expression
I B Bayer-Garner et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(10), 1052-1058 (2001-10-13)
Syndecan-1 (CD138) mediates myeloma cell adhesion, and loss of syndecan-1 from the cell surface may contribute to myeloma proliferation and dissemination. Flow cytometry analysis of myeloma cells in bone marrow specimens shows heterogeneity in cell surface syndecan-1 expression. It is
Lluís Colomo et al.
The American journal of surgical pathology, 28(6), 736-747 (2004-05-29)
Plasmablastic lymphoma was initially described as a variant of diffuse large B-cell lymphoma (DLBCL) involving the oral cavity of HIV+ patients and characterized by immunoblastic morphology and a plasma cell phenotype. However, other lymphomas may exhibit similar morphologic and immunophenotypic
M Chilosi et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 12(12), 1101-1106 (2000-01-05)
Detection of abnormal numbers and/or distribution of bone marrow (BM) plasma cells (PCs) on trephine biopsies can be important in the differential diagnosis of multiple myeloma (MM) and other PC disorders. A variety of immunohistochemical markers can potentially improve the

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