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SLX4

SLX4 structure-specific endonuclease subunit

Synonimy:
BTBD12, FANCP, MUS312
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(84464) Summary: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011]
  • Mouse(52864) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • Rat(302953) SLX4 structure-specific endonuclease subunit
  • Zebrafish(100001183) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • Horse(100069533) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • domestic cat(101095218) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • chicken(416665) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • dog(479867) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • cow(512193) SLX4 structure-specific endonuclease subunit
  • sheep(101123086) SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
  • domestic guinea pig(100718161) SLX4 structure-specific endonuclease subunit
  • naked mole-rat(101709821) SLX4 structure-specific endonuclease subunit

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SLX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-SLX4, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting human SLX4,
Gatunek
human
MISSION® esiRNA, targeting mouse Slx4,
Gatunek
mouse