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Merck

SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

Synonimy:
OAT4L, RST, URAT1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
  • Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
  • Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
  • dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
  • naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
  • cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
  • sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-SLC22A12 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-SLC22A12 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-SLC22A12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
(±)-Sulfinpyrazone, analytical standard,
Gatunek
human
Sulfinpyrazone, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Benzbromarone, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Benzbromarone, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Gatunek
human
Lesinurad, ≥98% (HPLC),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SLC22A12,
Gatunek
human