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RRM2B

ribonucleotide reductase M2 B (TP53 inducible)

Synonimy:
MTDPS8A, MTDPS8B, P53R2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(50484) Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
  • Mouse(382985) ribonucleotide reductase M2 B (TP53 inducible)
  • Rat(299976) ribonucleotide reductase M2 B (TP53 inducible)
  • cow(528960) ribonucleotide reductase M2 B (TP53 inducible)
  • sheep(101123639) ribonucleotide reductase M2 B (TP53 inducible)
  • naked mole-rat(101718446) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic guinea pig(100715485) ribonucleotide reductase M2 B (TP53 inducible)
  • Zebrafish(368909) ribonucleotide reductase M2 b
  • chicken(420253) ribonucleotide reductase M2 B (TP53 inducible)
  • Horse(100062030) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic cat(101099777) ribonucleotide reductase M2 B (TP53 inducible)
  • dog(481988) ribonucleotide reductase M2 B (TP53 inducible)

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-P53R2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-RRM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Monoclonal Anti-RRM2B antibody produced in mouse, clone 6C1, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Opis
Gatunek
Hydroxycarbamide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Hydroxyurea, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Hydroxycarbamide, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Hydroxyurea, 98%, powder,
Gatunek
human
Gemcitabine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting human RRM2B,
Gatunek
human