Przejdź do zawartości
Merck

PYCARD

PYD and CARD domain containing

Synonimy:
ASC, CARD5, TMS, TMS-1, TMS1
Gatunek:
Human PYCARD (29108), Mouse Pycard (66824), Rat Pycard (282817), Zebrafish pycard (57923), dog PYCARD (489925), domestic cat PYCARD (101088449), cow PYCARD (282846), sheep PYCARD (101105208), Goat PYCARD (100861338), domestic guinea pig Pycard (100734858)
Identyfikator UniProtKB:
Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8
Identyfikator genu:
  • Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(66824) PYD and CARD domain containing
  • Rat(282817) PYD and CARD domain containing
  • Zebrafish(57923) PYD and CARD domain containing
  • dog(489925) PYD and CARD domain containing
  • domestic cat(101088449) PYD and CARD domain containing
  • cow(282846) PYD and CARD domain containing
  • sheep(101105208) PYD and CARD domain containing
  • Goat(100861338) PYD and CARD domain containing
  • domestic guinea pig(100734858) PYD and CARD domain containing

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
PRS2287
Anti-ASC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry
immunohistochemistry
western blot
SAB4501315
Anti-ASC antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
SAB2500123
Anti-ASC/TMS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
HPA054496
Anti-PYCARD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
HPA049074
Anti-PYCARD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU066851
MISSION® esiRNA, targeting human PYCARD,
Gatunek
human