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POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

Synonimy:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
  • Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
  • domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
  • dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-POLR2A, (N-terminal) antibody produced in mouse, clone IF17, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Przeciwciało anty-POLR2A, klon 1F5, clone 1F5, from rat,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunocytochemistry

western blot
Przeciwciało anty-fosfo RNA Pol II (Ser7), klon 3D4A12, clone 3D4A12, 1 mg/mL, from rat,
Reaktywność gatunkowa
canine, human, monkey, mouse, rat
Zastosowanie
ChIP
ELISA

immunocytochemistry

western blot
Anti-phospho-RNAPII Antibody (Thr4), clone 1G7, clone 1G7, from rat,
Reaktywność gatunkowa
human, mouse, yeast
Zastosowanie
ChIP
immunocytochemistry

immunoprecipitation (IP)

western blot
Anty-Phospho-POLR2A-S7, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Proteins

Numer produktu
Opis
Gatunek
RNA Polymerase II, C-terminal human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
Gatunek
human
RNA Polymerase II, C-terminal domain, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human POLR2A,
Gatunek
human
MISSION® esiRNA, targeting mouse Polr2a,
Gatunek
mouse