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Merck

MAP3K1

mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

Synonimy:
MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4214) Summary: The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
  • Mouse(26401) mitogen-activated protein kinase kinase kinase 1
  • Rat(116667) mitogen activated protein kinase kinase kinase 1
  • sheep(101112260) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • domestic guinea pig(100723456) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • naked mole-rat(101720769) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • Domestic Rabbit(100328655) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • Zebrafish(100334486) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • chicken(427144) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • cow(523962) mitogen-activated protein kinase kinase kinase 1
  • Horse(100061688) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • domestic cat(101090328) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
  • dog(478061) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-MAP3K1 antibody produced in mouse, clone 2F6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay

western blot
Anti-MAP3K1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Anti-MAP3K1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-MEKKK 1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
western blot
Anti-phospho-MAP3K1 (pThr1402) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
PD 98,059, solid,
Gatunek
human
Adenine, BioReagent, suitable for cell culture,
Gatunek
human, rat, mouse
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Gatunek
human, rat, mouse
Adenine, ≥99%,
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
MEKK1 (664-1512), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Map3k1,
Gatunek
mouse
MISSION® esiRNA, targeting human MAP3K1,
Gatunek
human