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Merck

KCNA3

potassium voltage-gated channel, shaker-related subfamily, member 3

Synonimy:
HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3738) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16491) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Rat(29731) potassium voltage-gated channel, shaker-related subfamily, member 3
  • sheep(101105466) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Domestic Rabbit(100328945) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic guinea pig(100721847) potassium voltage-gated channel, shaker-related subfamily, member 3
  • naked mole-rat(101719045) potassium voltage-gated channel, shaker-related subfamily, member 3
  • chicken(404303) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic cat(101092201) potassium voltage-gated channel, shaker-related subfamily, member 3
  • cow(525507) potassium voltage-gated channel, shaker-related subfamily, member 3
  • dog(490110) potassium voltage-gated channel, shaker-related subfamily, member 3

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-KCNA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoclonal Anti-KCNA3 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-Potassium Channel Kv1.3 Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-Potassium Channel Kv1.3 Antibody, extracellular domain, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
western blot
Anti-phospho-Kv1.3/KCNA3 (pTyr135) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Charybdotoxin, ≥90% (HPLC),
Gatunek
mouse, rat, human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
Gatunek
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Gatunek
human
Guanidine hydrochloride, anhydrous, free-flowing, Redi-Dri, ≥99%,
Gatunek
human
Dalfampridine, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human KCNA3,
Gatunek
human