Przejdź do zawartości
Merck

HAP1

huntingtin-associated protein 1

Synonimy:
HAP2, HIP5, HLP, hHLP1
Gatunek:
Human HAP1 (9001), Mouse Hap1 (15114), Rat Hap1 (29430), dog HAP1 (607751), cow HAP1 (618422), domestic cat HAP1 (101088631), sheep HAP1 (101108406)
Identyfikator UniProtKB:
P54257, A8MQB5, O75358, Q59GK4, Q9H4G3, Q9HA98, Q9NY90
Identyfikator genu:
  • Human(9001) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15114) huntingtin-associated protein 1
  • Rat(29430) huntingtin-associated protein 1
  • dog(607751) huntingtin-associated protein 1
  • cow(618422) huntingtin-associated protein 1
  • domestic cat(101088631) huntingtin-associated protein 1
  • sheep(101108406) huntingtin-associated protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB2500503
Anti-HAP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
SAB1409968
Anti-HAP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
SAB1411596
Anti-HAP1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
MABN2456
Przeciwciało anty-HAP1, klon 1B6, clone 1B6, from mouse,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU094311
MISSION® esiRNA, targeting human HAP1,
Gatunek
human
EMU054451
MISSION® esiRNA, targeting mouse Hap1,
Gatunek
mouse