DNASE1
deoxyribonuclease I
Synonimy:
DNL1, DRNI
Gatunek:
Human DNASE1 (1773), Mouse Dnase1 (13419), Rat Dnase1 (25633), Zebrafish dnase1 (436947), dog DNASE1 (403413), domestic cat DNASE1 (101096195), cow DNASE1 (282217), Horse DNASE1 (100034219), chicken DNASE1 (395725), sheep DNASE1 (101122154) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(13419) deoxyribonuclease I
- Rat(25633) deoxyribonuclease I
- Zebrafish(436947) deoxyribonuclease I
- dog(403413) deoxyribonuclease I
- domestic cat(101096195) deoxyribonuclease I
- cow(282217) deoxyribonuclease I
- Horse(100034219) deoxyribonuclease I
- chicken(395725) deoxyribonuclease I
- sheep(101122154) deoxyribonuclease I
- Domestic Rabbit(100009513) deoxyribonuclease I
- naked mole-rat(101713435) deoxyribonuclease I
- domestic guinea pig(100718441) deoxyribonuclease I
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, human, rat
Zastosowanie
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Reaktywność gatunkowa
bovine, human, rat
Zastosowanie
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Reaktywność gatunkowa
bovine, human, rat
Zastosowanie
Anti-DNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Proteins
Numer produktu
Opis
Gatunek
Deoxyribonuclease I bovine, recombinant, expressed in Pichia pastoris, lyophilized powder, RNAse and protease, free,
Gatunek
Deoxyribonuclease I from bovine pancreas, lyophilized powder, Protein ≥85 %, ≥400 Kunitz units/mg protein,
Gatunek
Deoxyribonuclease I from bovine pancreas, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Gatunek
Deoxyribonuclease I from bovine pancreas, Standardized vial containing 2,000 Kunitz units of DNase I (D4527), vial of ≥0.25 mg total protein,
Gatunek