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Merck

DDR2

discoidin domain receptor tyrosine kinase 2

Synonimy:
MIG20a, NTRKR3, TKT, TYRO10
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(18214) discoidin domain receptor family, member 2
  • Rat(685781) discoidin domain receptor tyrosine kinase 2
  • Zebrafish(559428) discoidin domain receptor family, member 2
  • dog(478987) discoidin domain receptor tyrosine kinase 2
  • chicken(396404) discoidin domain receptor tyrosine kinase 2
  • Horse(100058300) discoidin domain receptor tyrosine kinase 2
  • cow(533523) discoidin domain receptor tyrosine kinase 2
  • domestic cat(101085267) discoidin domain receptor tyrosine kinase 2
  • sheep(101109754) discoidin domain receptor tyrosine kinase 2
  • naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
  • domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2

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ELISA

Numer produktu
Opis
Gatunek
Phosphotyrosine DDR2 / Discoidin domain-containing Receptor 2 ELISA Kit, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
MONOCLONAL ANTI-DDR2 antibody produced in mouse, clone 484CT5.5.4, crude ascites, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Monoclonal Anti-DDR2 antibody produced in mouse, clone 3B11E4, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-DDR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Ddr2,
Gatunek
mouse
MISSION® esiRNA, targeting human DDR2,
Gatunek
human
MISSION® esiRNA, targeting mouse Ddr2,
Gatunek
mouse