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ALOX5AP

arachidonate 5-lipoxygenase-activating protein

Synonimy:
FLAP
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(241) Summary: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(11690) arachidonate 5-lipoxygenase activating protein
  • Rat(29624) arachidonate 5-lipoxygenase activating protein
  • naked mole-rat(101704126) arachidonate 5-lipoxygenase-activating protein
  • domestic guinea pig(100733727) arachidonate 5-lipoxygenase-activating protein
  • Zebrafish(337376) arachidonate 5-lipoxygenase-activating protein
  • domestic cat(101090316) arachidonate 5-lipoxygenase-activating protein
  • cow(613869) arachidonate 5-lipoxygenase-activating protein
  • Horse(100034178) arachidonate 5-lipoxygenase-activating protein
  • dog(477323) arachidonate 5-lipoxygenase-activating protein
  • chicken(770904) arachidonate 5-lipoxygenase-activating protein

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ALOX5AP (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-FLAP Antibody, clone 2S7Z0, Rabbit Monoclonal, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-FLAP/ALOX5AP, C-Terminal antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-FLAP/ALOX5AP (Internal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-ALOX5AP (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
BW B70C, >98% (HPLC), solid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ALOX5AP,
Gatunek
human
MISSION® esiRNA, targeting mouse Alox5ap,
Gatunek
mouse