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Merck

AIRE

autoimmune regulator

Synonimy:
AIRE1, APECED, APS1, APSI, PGA1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
  • Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • Rat(294328) autoimmune regulator
  • Zebrafish(100007662) autoimmune regulator
  • cow(784775) autoimmune regulator
  • domestic cat(101091039) autoimmune regulator
  • dog(487796) autoimmune regulator
  • chicken(429666) autoimmune regulator
  • naked mole-rat(101725873) autoimmune regulator
  • domestic guinea pig(100729880) autoimmune regulator
  • sheep(101102698) autoimmune regulator

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-AIRE (Isoforms 1 and 2) (AB1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ChIP
ELISA

western blot
Anti-AIRE Antibody, clone Mab155, clone Mab155, 1 mg/mL, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

western blot
Anti-AIRE Antibody, clone 5H12, clone 5H12, from rat,
Reaktywność gatunkowa
mouse
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AIRE Antibody, Upstate®, from rabbit,
Reaktywność gatunkowa
mouse
Zastosowanie
western blot
Anti-AIRE antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Aire,
Gatunek
mouse
MISSION® esiRNA, targeting human AIRE,
Gatunek
human