Effective and Efficient Design of a Downstream Purification Process for Plasmid DNA

Nargisse El Hajjami, Ph.D. Eng. is a senior consultant for novel modalities and the global lead for mRNA technology within our bioprocessing strategy operationalization group. Nargisse is a molecular microbiologist and bioprocess expert with 11 years of experience combining scientific research, process development, and biomanufacturing engineering. In her current role, Nargisse focuses on novel modalities business development by leading strategic initiatives, supporting go-to-market strategies, providing directions to operationalize the business strategy, as well as supporting customers to build, grow, and optimize their manufacturing processes.

Tom currently manages the MSAT Americas purification process engineering team, which is responsible for supporting end-users of Merck's solutions for chromatography, TFF, single-use, and systems technologies. Tom received his B.S. in chemical engineering from Northeastern University.

Laurens Vergauwen is an EMEA process development scientist and a global vaccine and viral therapies process development focal point lead. In this role, Laurens supports customers in the development and optimization of various downstream purification technologies (chromatography, TFF, clarification, sterile and viral filtration). Being able to work with different types of manufacturers has enabled him to gain knowledge about purification strategies for various biopharmaceuticals, including mRNA. He obtained his M.S. in industrial biochemical engineering at the University of Leuven (Belgium).