673277
2-Methyltetrahydrofuran
BioRenewable, anhydrous, ≥99%, Inhibitor-free
Synonym(s):
2-MeTHF, Tetrahydro-2-methylfuran, Tetrahydrosilvan
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About This Item
Empirical Formula (Hill Notation):
C5H10O
CAS Number:
Molecular Weight:
86.13
Beilstein:
102448
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
grade
anhydrous
Quality Level
Assay
≥99%
form
liquid
expl. lim.
0.34-6.3 % (lit.)
greener alternative product characteristics
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
impurities
≤0.002% water
≤0.005% water (100 mL pkg)
evapn. residue
≤0.0003%
refractive index
n20/D 1.406 (lit.)
bp
78-80 °C (lit.)
mp
-136 °C (lit.)
density
0.86 g/mL at 25 °C (lit.)
SMILES string
CC1CCCO1
InChI
1S/C5H10O/c1-5-3-2-4-6-5/h5H,2-4H2,1H3
InChI key
JWUJQDFVADABEY-UHFFFAOYSA-N
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General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.
2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahydrofuran, is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis. It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether. The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide.
2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahydrofuran, is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis. It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether. The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide.
Application
2-Methyltetrahydrofuran may be used as a solvent for phosphatidylserine synthesis.
It may be used as an alternative solvent to:
Organic Solar Cells
2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry
It may be used as an alternative solvent to:
- Dimethyl sulfoxide (DMSO) or methyl tert-butyl ether (MTBE) in the C-C bond forming reactions catalyzed by lyase enzyme.
- Tetrahydrofuran (THF) in the reaction between Grignard reagents and carbonyl compounds.
- Methylene chloride in some biphasic reactions.
Organic Solar Cells
2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry
Features and Benefits
Greener alternative for THF, DCM, DMSO, and MTBE
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
14.0 °F - closed cup
Flash Point(C)
-10.0 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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