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Key Documents

SAB4300471

Sigma-Aldrich

Anti-CTNNB1 (Ab-37) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CTNNB antibody produced in rabbit, Anti-DKFZp686D02253 antibody produced in rabbit, Anti-FLJ25606 antibody produced in rabbit, Anti-FLJ37923 antibody produced in rabbit, Anti-catenin (cadherin-associated protein), beta 1, 88kDa antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~92 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(I-H-S-G-A)

NCBI accession no.

NP_001091679.1

UniProt accession no.

P35222

application(s)

research pathology

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CTNNB1(1499)

Immunogen

Peptide sequence around aa. 35-39 (I-H-S-G-A), according to the protein CTNNB1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Livia M Mermejo et al.
Clinical endocrinology, 81(4), 503-510 (2014-04-11)
The role of planar cell polarity (Wnt/PCP) and calcium-dependent (Wnt/Ca) noncanonical Wnt pathways in adrenocortical tumours (ACTs) is unknown. To investigate the gene expression of Wnt/PCP and Wnt/Ca pathways and its association with TP53 p.R337H and CTNNB1 mutations in paediatric
Catherine M Willis et al.
PloS one, 9(8), e103966-e103966 (2014-08-05)
Expression of the glycosaminoglycan chondroitin sulfate-E (CS-E) is misregulated in many human cancers, including breast cancer. Cell-surface associated CS-E has been shown to have pro-tumorigenic functions, and pharmacological treatment with exogenous CS-E has been proposed to interfere with tumor progression

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