SRP6560
Wnt-2 human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym(s):
INT1L1, IRP, Int-1-like protein 1, Int-1-related protein
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
Recommended Products
biological source
human
recombinant
expressed in E. coli
Assay
≥90% (SDS-PAGE)
form
lyophilized
mol wt
39.9 kDa
packaging
pkg of 1 mg
pkg of 10 μg
pkg of 50 μg
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... WNT2(7472)
Biochem/physiol Actions
Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt family member-2 (Wnt-2) has a role in activating β-catenin. It has been shown to have a role in cardiogenesis. The protein is overexpressed in tumors and cancers.
Physical form
Lyophilized without additives.
Reconstitution
Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Wnt signal transduction pathways
Yuko Komiya
Organogenesis, 4(2), 68-75 (2008)
Overexpression of Wnt-2 in colorectal cancers.
Park JK
Neoplasma, 56(2), 119-123 (2009)
Wnt2 is a direct downstream target of GATA6 during early cardiogenesis
Alexander A
Mechanisms of Development, 123, 297-311 (2006)
Wnt2 complements Wnt/?-catenin signaling in colorectal cancer
Youn-Sang Jung
Oncotarget, 6(35), 37257-37268 (2015)
Wnt2 as a new therapeutic target in malignant pleural mesothelioma
Julien Mazieres
International Journal of Cancer. Journal International Du Cancer (2005)
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