Skip to Content
Merck
All Photos(1)

Key Documents

SRP6542

Sigma-Aldrich

FNDC5

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym(s):

Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Assay

≥95% (SDS-PAGE)

form

lyophilized

mol wt

~160 kDa

packaging

pkg of 10 μg

impurities

<0.1 EU/μg endotoxin (LAL test)

UniProt accession no.

Q8NAU1

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... FNDC5(252995)

General description

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
extracellular domain, human aa 32-152 / mouse aa 29-149 is untagged. FNDC5 extracellular domain has 100% identity between human, mouse and rat.

Physical form

Lyophilized in PBS.

Reconstitution

Reconstitute with 100 μsterile distilled water.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service