Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

SML2556

Sigma-Aldrich

Pt-ttpy

>97% (NMR)

Synonym(s):

(SP-4-2)-Chloro[4′-(4-methylphenyl)-2,2′:6′,2′′-terpyridine-κN1,κN1′,κN1′′]-Platinum(1+) chloride, Tolylterpyridin-platin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H17Cl2N3Pt
CAS Number:
727721-37-1
Molecular Weight:
589.37
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

>97% (NMR)

form

powder

color

faint yellow to dark orange

solubility

DMSO: 0.2 mg/mL (warmed)

storage temp.

2-8°C

SMILES string

CC1=CC=C(C2=CC(C3=[N+]4C=CC=C3)=[N+]5C(C6=CC=CC=[N+]6[Pt-2]54Cl)=C2)C=C1.[Cl-]

Biochem/physiol Actions

Pt-ttpy, a metallo-organic complex, is a G-quadruplex ligand that potently induces significant telomere-associated DNA damage in cancer cells. It inhibits telomerase and/or telomere functions. Pt-ttpy induces number of chromatin defects in mitosis including chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service