SAE0004
Kynurenine 3-Monooxygenase, Pseudomonas fluorescens (strain 17400), Recombinant
Synonym(s):
KMO
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form
solution
Quality Level
specific activity
≥3 U/mg
mol wt
50,712 Da
shipped in
dry ice
storage temp.
−70°C
General description
Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan metabolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a 1:1 ratio of co-factor to protein.
Unit Definition
1 unit will oxidize L-kynurenine at 1 mol/min at pH 7.0, 25°C.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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