SAB5700456

Anti-Phospho-PPP1CA-T320 antibody produced in rabbit

• Synonym(s): PP-1A, PP1A, PP1alpha, PPP1A, PPP1CA
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 32; 37; 38
• species reactivity: mouse, human, rat
• concentration: 2.36 mg/ml
• technique(s): immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• UniProt accession no.: P62136
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr320)
• Gene Information: human ... PPP1CA(5499)

Description

General description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding T320 of human PPP1CA

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable