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Key Documents

S9991

Sigma-Aldrich

Recombinant SARS-CoV-2 nucleocapsid protein

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About This Item

UNSPSC Code:
12352202

form

frozen liquid

Quality Level

storage condition

avoid repeated freeze/thaw cycles

technique(s)

ELISA: suitable
lateral flow assay: suitable

storage temp.

−70°C

General description

This Nucleoprotein (nucleocapsid protein) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is expressed in insect cells. The Nucleocapsid protein is not important for determination of neutralizing IgG antibodies. However, the recombinant SARS-CoV-2 Nucleocapsid Protein, S9991 antigen in combination with monoclonal antibodies directed against neutralizing epitopes such as the ACE2 binding domain could be used in a competitive setup for determining neutralizing antibodies. The nucleocapsid protein is quite conserved. Using nucleocapsid protein for acute / early antibodies such as IgA/ IgM should make it possible to detect antibodies directed against the variants of concern in a satisfactory way at an early stage of illness.
For IgM detection, a mixture of nucleocapsid and spike proteins is recommended.

Physical form

sab5700595

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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