S2067
S9 from Liver, Pooled
from rat(Sprague-Dawley), male
Synonym(s):
Liver S9 Fraction, S9 Liver Extract
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About This Item
UNSPSC Code:
12161501
NACRES:
NA.47
biological source
rat (Sprague-Dawley)
Quality Level
packaging
vial of ~20 mg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
rat ... Mrps9(301371)
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Application
S9 from Liver, Pooled has been used in metabolic activation in Salmonella typhimurium strains.
Biochem/physiol Actions
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Genotoxicity evaluation of locally produced dental porcelain-An in vitro study using the Ames and Comet assays
Noushad M, et al.
Toxicology in vitro, 23(6), 1145-1150 (2009)
The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 46(3), 169-172 (2001)
Milena Lopes Francisco Bittencourt et al.
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