P9511
3-sn-Phosphatidic acid sodium salt from egg yolk lecithin
≥98%
Synonym(s):
1,2-Diacyl-sn-glycero-3-phosphate sodium salt, L-α-Phosphatidic acid sodium salt, PA
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Recommended Products
Quality Level
Assay
≥98%
form
powder
storage temp.
−20°C
SMILES string
[Na+].[Na+].OC[C@@H](O)COP([O-])([O-])=O
InChI
1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2/t3-;;/m1../s1
InChI key
GEKBIENFFVFKRG-HWYNEVGZSA-L
Looking for similar products? Visit Product Comparison Guide
General description
Phosphatidic acid is obtained from phosphatidylcholine with the help of phospholipase D.
Application
3-sn-Phosphatidic acid sodium salt from egg yolk lecithin
- in the reaction mixture for CDS (cytidine triphosphate:phosphatidate cytidyltransferase) assay and reference lipid for thin layer chromatography (TLC)
- as a standard to compare the generated radiolabeled phosphatidic acid (PA)
- to examine its effects on At-Rac2–associated kinase activity
Biochem/physiol Actions
Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol, phosphatidic acid and lysophosphatidic acid.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases, Phosphoinositide Kinases and Phosphoprotein Phosphatases (Serine/Threonine) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Prepared from L-α-phosphatidylcholine by hydrolysis with cabbage phospholipase D.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Phosphatidic acid and phospholipase D both stimulate phosphoinositide turnover in cultured human keratinocytes
Ryder NS, et al.
Cellular Signalling, 5(6), 787-794 (1993)
Stefano Mancuso et al.
Plant signaling & behavior, 2(4), 240-244 (2007-07-01)
Auxin (IAA) is versatile signalling molecule of plants, currently classified as plant hormone. But there are data suggesting that auxin is acting also as plant-specific morphogen, electric-responses inducing transmitter, and as general signalling molecule used for plant-bacteria communication. Our previous
Glycerolipids in signal transduction
Lambeth JD, et al.
New Biotechnology, 31, 237-255 (1996)
Daniel Pastor-Flores et al.
Biochimica et biophysica acta, 1861(3), 249-259 (2016-01-09)
Pkh is the yeast ortholog of the mammalian 3-phosphoinositide-dependent protein kinase 1 (PDK1). Pkh phosphorylates the activation loop of Ypks, Tpks, Sch9 and also phosphorylates the eisosome components Lsp1 and Pil1, which play fundamental roles upstream of diverse signaling pathways
Alexandre Francou et al.
Development (Cambridge, England), 141(22), 4320-4331 (2014-11-06)
Elongation of the vertebrate heart occurs by progressive addition of second heart field (SHF) cardiac progenitor cells from pharyngeal mesoderm to the poles of the heart tube. The importance of these cells in the etiology of congenital heart defects has
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service