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P7539

Sigma-Aldrich

Penicillin–Streptomycin Solution Hybri-Max™

with 10,000 units penicillin and 10mg/ml streptomycin in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for hybridoma

Synonym(s):

Pen-Strep

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About This Item

UNSPSC Code:
12352207

Quality Level

300

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes
protein synthesis | interferes

shipped in

dry ice

storage temp.

−20°C

Related Categories

General description

Penicillin-Streptomycin is used to supplement cell culture media to control bacterial contamination.

Application

Penicillin–Streptomycin Solution Hybri-Max™ has been used:
  • as a supplement in Roswell Park Memorial Institute (RPMI) 1640 medium to maintain human breast cancer cell lines
  • as a component of the Dulbecco′s modified Eagle′s medium/F-12 (DMEM/F-12) to culture human chondrocytes
  • as a component of the DMEM medium to culture human hepatocyte carcinoma cells

Other Notes

20ml,100ml
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chun-Yen Sung et al.
Biofabrication, 7(4), 045007-045007 (2015-12-20)
In this study, we describe the development of surface-modified chitosan substrates to examine topographically related Neuro-2a cell behaviors. Different functional groups can be modified on chitosan surfaces to probe Neuro-2a cell morphology. To prepare chitosan substrates with micro/nano-scaled features, we
Casper Bindzus Foldager et al.
Cartilage, 7(1), 52-61 (2016-03-10)
To identify the collagen type IV (Col4) isoform in articular cartilage and to evaluate the expressions of Col4 and laminin in the pericellular matrix (PCM) in damaged cartilage and during cartilage repair. The Col4 isoform was determined in chondrocytes isolated
Jessica Roos et al.
Antioxidants & redox signaling, 28(14), 1265-1285 (2017-07-13)
5-Lipoxygenase (5-LO) is the key enzyme of leukotriene (LT) biosynthesis and is critically involved in a number of inflammatory diseases such as arthritis, gout, bronchial asthma, atherosclerosis, and cancer. Because 5-LO contains critical nucleophilic amino acids, which are sensitive to
Naoya Nakai et al.
FEBS open bio, 10(10), 2149-2156 (2020-09-04)
Proteolysis is known to play a crucial role in maintaining skeletal muscle mass and function. Autophagy is a conserved intracellular process for the bulk degradation of proteins in lysosomes. Although nutrient starvation is known to induce autophagy, the effect of
Chella Krishna Vadivel et al.
Cancers, 13(2) (2021-01-21)
Perturbation in JAK-STAT signaling has been reported in the pathogenesis of cutaneous T cell lymphoma (CTCL). JAK3 is predominantly associated with the intra-cytoplasmic part of IL-2Rγc located in the plasma membrane of hematopoietic cells. Here we demonstrate that JAK3 is

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