GE17-0978-02

Butyl-s Sepharose^™ 6 Fast Flow

Cytiva 17-0978-02, pack of 200 mL

• UNSPSC Code: 41106500
• NACRES: NA.56

Properties

• ligand: butyl-S
• shelf life: Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
• packaging: pack of 200 mL
• manufacturer/tradename: Cytiva 17-0978-02
• matrix: 6% cross-linked agarose
• particle size: 45-165 μm
• average diameter: 90 μm
• cleaning in place: 2-14
• working range: 3-13
• suitability: suitable for bioprocess medium

Description

General description

Butyl-S Sepharose^™ 6 Fast FLow is the least hydrophobic medium in the Sepharose^™ Fast FLow hydrophobic interaction chromatography (HIC) range and is particularly useful during the initial stages of a purification process to remove the bulk of impurities.

Application

Butyl-S Sepharose^™ 6 Fast FLow is part of the Sepharose^™ Fast FLow HIC platform, which has been an industrial standard for HIC chromatography during recent decades. Butyl-S Sepharose^™ 6 Fast FLow is composed of cross-linked 6% Agarose beads modified with butyl groups via a thio-ether linkage. It will exhibit a different selectivity compared to Butyl Sepharose^™ 4 Fast FLow and other HIC Sepharose^™ Fast FLow products.

This resin is designed for the binding and elution of relatively strong hydrophobic molecules at comparatively Low salt concentrations. Butyl?S Sepharose^™ 6 Fast FLow is particularly useful during the initial stages of a separation process to remove the bulk of impurities without stringent requirements for conditioning of the sample (e.g. adjustment of pH, salt concentration etc.)

Butyl-S Sepharose^™ 6 Fast FLow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Butyl-S Sepharose^™ 6 Fast FLow meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

• Binds and elutes relatively strong hydrophobic molecules at comparatively Low salt concentrations
• The least hydrophobic medium in the well proven Sepharose^™ Fast FLow HIC range
• Purifies recombinant Hepatitis B virus surface antigen from CHO cells
• Developed and optimized in cooperation with a process-scale manufacturer of biopharmaceuticals
• The hydrophilic nature of the base matrix ensures Low levels of non-specific binding.

Storage and Stability

Store at 4 to 30 °C (20% Ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Sepharose is a trademark of Cytiva

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Statements: H226
• Precautionary Statements: P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501
• Storage Class Code: 3 - Flammable liquids