C7519
Choline bicarbonate
~80% in H2O
Synonym(s):
2-Hydroxyethyl)trimethylammonium bicarbonate
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About This Item
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form
liquid
Quality Level
concentration
~80% in H2O
density
1.17 g/mL at 25 °C (lit.)
lipid type
phospholipids
storage temp.
2-8°C
SMILES string
OC([O-])=O.C[N+](C)(C)CCO
InChI
1S/C5H14NO.CH2O3/c1-6(2,3)4-5-7;2-1(3)4/h7H,4-5H2,1-3H3;(H2,2,3,4)/q+1;/p-1
InChI key
DQKGOGJIOHUEGK-UHFFFAOYSA-M
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Application
Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.
Biochem/physiol Actions
Acyl group acceptor
Substrates
Choline acetyltransferase substrate
Other Notes
Note: The bicarbonate converts to the carbonate with release of CO2 on aging.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Transdermal delivery of pharmaceuticals using ionic liquids and deep eutectic solvents (DES) has attracted significant interest due to the inherent tunability of the molecules and their capacity to transport large molecules across the skin. Several key properties of DESs including
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Transdermal delivery of large hydrophilic molecules is a long-standing challenge owing to the strong diffusive barrier properties of the skin. Using choline and geranic acid (CAGE) based ionic liquid (IL) as a delivery technology, we report a significant improvement of
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