B9186

Anti-Brain-derived Neurotrophic Factor antibody produced in chicken

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-BDNF, Anti-MGC34632
• MDL number: MFCD01633045
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: chicken
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): flow cytometry: 3-10 μg/mL; immunohistochemistry: 0.1-1.0 μg/mL using free-floating sections; immunohistochemistry: 0.5-5 μg/mL
• UniProt accession no.: P23560
• storage temp.: −20°C
• Gene Information: human ... BDNF(627)

Description

Immunogen

purified, Sf21-derived, recombinant human brain-derived neurotrophic factor.

Biochem/physiol Actions

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves