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Key Documents

AV32587

Sigma-Aldrich

Anti-KLF15 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Klf15 Antibody, Klf15 Antibody - Anti-KLF15 antibody produced in rabbit, Anti-Kruppel-like factor 15

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

44 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_054798

UniProt accession no.

Q9UIH9

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KLF15(28999)

Immunogen

Synthetic peptide directed towards the N terminal region of human KLF15

Application

Rabbit Anti-KLF15 antibody can be used for western blot applications at a concentration of 1.0-2.0μg/ml. It can also be used for immunohistochemical applications at a concentration of 4-8μg/ml using paraffin-embedded tissues.

Biochem/physiol Actions

KLF15 is a Cys2-His2 zinc finger gene. It is found abundantly expressed in the liver, kidneys, heart, and skeletal muscle.

Sequence

Synthetic peptide located within the following region: DASSPCSCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGS

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Susan Gray et al.
The Journal of biological chemistry, 277(37), 34322-34328 (2002-07-05)
Resistance to the stimulatory effects of insulin on glucose utilization is a key feature of type 2 diabetes, obesity, and the metabolic syndrome. Recent studies suggest that insulin resistance is primarily caused by a defect in glucose transport. GLUT4 is
Joji Yamamoto et al.
The Journal of biological chemistry, 279(17), 16954-16962 (2004-02-13)
Acetyl-CoA synthetase 2 (AceCS2) produces acetyl-CoA for oxidation through the citric acid cycle in the mitochondrial matrix. AceCS2 is highly expressed in the skeletal muscle and is robustly induced by fasting. Quantification of AceCS2 transcripts both in C2C12 and human
Toshiyuki Mori et al.
The Journal of biological chemistry, 280(13), 12867-12875 (2005-01-25)
Krüppel-like zinc finger transcription factors (KLFs) play diverse roles during cell differentiation and development in mammals. We have now shown by microarray analysis that expression of the KLF15 gene is markedly up-regulated during the differentiation of 3T3-L1 preadipocytes into adipocytes.
Lingling Wu et al.
Journal of cellular and molecular medicine, 25(12), 5691-5706 (2021-05-06)
Mesangial cell (MC) proliferation is a key pathological feature in a number of common human renal diseases, including mesangial proliferative nephritis and diabetic nephropathies. Knowledge of MC responses to pathological stimuli is crucial to the understanding of these disease processes.
Seung Seok Han et al.
International journal of molecular medicine, 42(3), 1593-1602 (2018-06-15)
Krüppel‑like factor 15 (KLF15), also known as kidney‑enriched transcription factor, is known to participate in podocyte differentiation. However, the role of KLF15 in chronic podocyte injury remains incompletely understood, particularly in proteinuric disease models. In the present study, the 5/6 nephrectomy

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