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39326

Sigma-Aldrich

N-[2-(Dansylamino)ethyl]maleimide

BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

Synonym(s):

N-(2-Maleimidoethyl)-5-dimethylamino-1-naphthalenesulfonamide, N-(2-Maleimidoethyl)dansylamide

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About This Item

Empirical Formula (Hill Notation):
C18H19N3O4S
CAS Number:
Molecular Weight:
373.43
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.32

product line

BioReagent

Assay

≥99.0% (HPLC)

fluorescence

λex 327 nm; λem 547 nm in 0.1 M phosphate pH 7.0, 2-mercaptoethanol

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCN3C(=O)C=CC3=O

InChI

1S/C18H19N3O4S/c1-20(2)15-7-3-6-14-13(15)5-4-8-16(14)26(24,25)19-11-12-21-17(22)9-10-18(21)23/h3-10,19H,11-12H2,1-2H3

InChI key

GFVSIWWKMOVBJL-UHFFFAOYSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Andreas Helmersson et al.
Plant physiology, 147(3), 1158-1167 (2008-05-30)
Zinc is a potent regulator of programmed cell death (PCD) in animals. While certain, cell-type-specific concentrations of intracellular free zinc are required to protect cells from death, zinc depletion commits cells to death in diverse systems. As in animals, PCD
Jun Yin et al.
Langmuir : the ACS journal of surfaces and colloids, 25(19), 11367-11374 (2009-08-28)
We report on the fabrication of Cu2+-sensing thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) microgels labeled with metal-chelating acceptor and fluorescent reporter moieties. Cu2+ detection sensitivity can be considerably enhanced via thermo-induced collapse of the sensing matrix, which can easily optimize the relative spatial
S Aoki et al.
Journal of the American Chemical Society, 123(6), 1123-1132 (2001-07-18)
A cyclen (=1,4,7,10-tetraazacyclododecane) doubly functionalized with three carbamoylmethyl groups and one dansylaminoethyl (dansyl = 2-(5-(dimethylamino)-1-naphthalenesulfonyl) group (L(2) = 1-(2-(5-(dimethylamino)-1-naphthalenesulfonylamido)ethyl)-4,7,10-tris(carbamoylmethyl)-cyclen) was synthesized and characterized. Potentiometrtic pH titration and UV spectrophotometric titration of L(2) served to determine deprotonation of the pendant dansylamide

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