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Key Documents

317R-1

Sigma-Aldrich

Cytokeratin 17 (EP98) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP98, monoclonal

description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

form

buffered aqueous solution

species reactivity

human

packaging

bottle of 1.0 mL predilute (317R-17)
bottle of 7.0 mL predilute (317R-18)
vial of 0.1 mL concentrate (317R-14)
vial of 0.5 mL concentrate (317R-15)
vial of 1.0 mL concentrate (317R-16)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... KRT17(3872)

Related Categories

General description

Cytokeratin 17 is 46 kD intermediate filament found in simple epithelia and is a marker for cervical reserve (stem) cells.1,2 CK17 can be useful in the identification of uterine cervical squamous lesions including atypical immature metaplasia, cervical intraepithelial neoplasia, and cervical squamous carcinoma.1-3 CK17 also assists in the differentiation of oral squamous cell carcinoma.4

Quality


IVD
IVD
IVD
RUO

Linkage

Cytokeratin 17 Positive Control Slides, Product No. 317S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Luisa F Escobar-Hoyos et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 27(4), 621-630 (2013-09-21)
Most previously described immunohistochemical markers of cervical high-grade squamous intraepithelial lesion (HSIL) and squamous cell carcinoma may help to improve diagnostic accuracy but have a minimal prognostic value. The goals of the current study were to identify and validate novel
Ryoji Kitamura et al.
Journal of cancer research and clinical oncology, 138(8), 1299-1310 (2012-04-03)
The aim of this study was to confirm the expression profile of cytokeratin (CK)17 in comparison with that of CK13 in oral squamous cell carcinoma (OSCC) and leukoplakia and to clarify an association of CK17 with the OSCC differentiation. The

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