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676934

Sigma-Aldrich

1,4-Dioxane

ACS reagent, ≥99.0%

Synonym(s):

Diethylene oxide, Dioxane

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About This Item

Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
123-91-1
Molecular Weight:
88.11
Beilstein:
102551
EC Number:
204-661-8
MDL number:
MFCD00006571
UNSPSC Code:
12352005
PubChem Substance ID:
329760662
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C)
40 mmHg ( 25 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

356 °F

expl. lim.

22 %

technique(s)

thin layer chromatography (TLC): suitable

impurities

≤0.0016 meq/g Titr. acid
≤0.005% Peroxide as (H2O2)
≤0.01% Carbonyl (as HCHO)
≤0.05% water

evapn. residue

≤0.005%

color

APHA: ≤20

refractive index

n20/D 1.422 (lit.)

pH

6.0-8 (20 °C, 500 g/L)

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

transition temp

freezing point ≥11.0

density

1.034 g/mL at 25 °C (lit.)

SMILES string

C1COCCO1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

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General description

1,4-Dioxane is widely used as a solvent for various organic compounds in industry. It is a non-biodegradable contaminant found in industrial effluents. Its oxidative degradation by using oxygen and ozone has been useful in converting it into biodegradable products, which can be easily removed by conventional methods.

Application

1,4-Dioxane may be employed as solvent in the synthesis of N-(4-(prop-2-ynyloxy)phenyl)acetamide and 3-(4-(prop-2-ynyloxy)phenyl)-3,4-dihydro-2H-benzo[e][1,3]oxazine.

Signal Word

Danger

Hazard Statements

H225 - H319 - H335 - H350

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019 - EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Certificates of Analysis (COA)

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Oxidation and biodegradability enhancement of 1,4-dioxane using hydrogen peroxide and ozone.
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