PHR2010

Pramipexole Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole, (S)-4,5,6,7-TETRAHYDROBENZO THIAZOLE-2,6-DIAMINE
• Empirical Formula (Hill Notation): C₇H₁₁N₃S
• CAS Number: 106092-09-5
• Molecular Weight: 169.25
• MDL number: MFCD07368003
• UNSPSC Code: 41116107

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1553768
• API family: pramipexole
• CofA: current certificate can be downloaded
• packaging: pkg of 50 mg
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: N[C@H]1CCc2nc(N)sc2C1
• InChI: 1S/C7H11N3S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h4H,1-3,8H2,(H2,9,10)/t4-/m0/s1
• InChI key: DRRYZHHKWSHHFT-BYPYZUCNSA-N

Description

General description

Pramipexole Related Compound A is an impurity of pramipexole, which is an aminobenzothiazole compound and non-ergoline dopamine agonist widely used in the treatment of Parkinson′s disease (PD).
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Pramipexole Dihydrochloride may be used as a secondary pharma standard for the determination of the analyte in pharmaceutical formulations using liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB4761 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable