03716

(±)-Lisofylline

analytical standard

• Synonym(s): Lisofylline, (±)-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine, 5-Hydroxy pentoxifylline, Penthydroxyfylline
• Empirical Formula (Hill Notation): C₁₃H₂₀N₄O₃
• CAS Number: 6493-06-7
• Molecular Weight: 280.32
• MDL number: MFCD00871850
• UNSPSC Code: 41116107
• PubChem Substance ID: 329747785
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥99.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: O=C1N(CCCCC(O)C)C(N(C)C2=C1N(C)C=N2)=O
• InChI: 1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3
• InChI key: NSMXQKNUPPXBRG-UHFFFAOYSA-N

Description

General description

Lisofylline (LSF) is a synthetically modified methylxanthine which is known to exhibit various therapeutic properties. It is a potent anti-inflammatory agent and an antioxidant with the ability to suppress oxygen radical production. LSF is used for treating acute lung injury and also has a role in the early treatment of diabetes.

Application

Lisofylline may be used as an analytical reference standard for the determination of the analyte in rat plasma by various high-performance liquid chromatography (HPLC) based techniques.

Recommended products

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable