biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, bovine, chicken, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... DES(1674)
Specificity
Desmin. Reacts specifically with desmin in cultured cells or tissue preparations originating from chicken, human, bovine and mouse tissue. AB907 specifically stains the wide desmin band in immunoblot at a molecular weight of 50-55 kD.
Immunogen
Purified desmin from chicken gizzard, isolated by modified procedure of Geisler, et al [J. Biol Chem. (1980). 111:425-433].
Application
Anti-Desmin Antibody is an antibody against Desmin for use in WB, IH(P).
Indirect immunofluorescence of formalin fixed paraffin-embedded sections of human intestine sections: 1:10-1:20.
Immunoblotting
Optimal working dilutions must be determined by the end user.
Immunoblotting
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Linkage
Replaces: 04-585
Physical form
Rabbit antiserum. Liquid containing 0.1% sodium azide as a preservative.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue.
Raymond, F; Metairon, S; Kussmann, M; Colomer, J; Nascimento, A; Mormeneo et al.
BMC Genomics null
E Lazarides et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(12), 4344-4348 (1976-12-01)
We report the immunological characterization of the subunit of the intermediate sized (100 A) filaments from muscle cells. The protein as isolated from smooth muscle (chicken gizzard) has an apparent molecular weight of 50,000. It is insoluble in buffers that
Richard Sharp et al.
Nature medicine, 8(11), 1276-1280 (2002-10-09)
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children, yet molecular events associated with the genesis and progression of this potentially fatal disease are largely unknown. For the molecules and pathways that have been implicated, genetic validation has been
Copurification of actin and desmin from chicken smooth muscle and their copolymerization in vitro to intermediate filaments.
Hubbard, B D and Lazarides, E
The Journal of cell biology, 80, 166-182 (1979)
Immunocytochemical localization of desmin at human neuromuscular junctions.
Askanas, V, et al.
Neurology, 40, 949-953 (1990)
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