AB3610

Anti-Survivin Antibody

serum, Chemicon^®

• Synonym(s): TIAP
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• NCBI accession no.: NM_001012270.1; NM_001012271.1; NM_001168.2
• UniProt accession no.: O15392
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... BIRC5(332)

Description

General description

Apoptosis is triggered by a variety of stimuli, including members of the Tumor Necrosis Factor (TNF) family, and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. One of these IAP proteins, Survivin/TIAP, interacts with the processed form of caspase-3 and has been shown to inhibit its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.

Immunogen

Recombinant, GST-tagged full length human Survivin

Application

Immunoblotting: Recommended antibody dilution 1:3000-6000

Immunoprecipitation: Recommended antibody dilution 1:200

Immunohistochemisty: Recommended antibody dilution 1:1500

Optimal antibody dilutions must be determined by end-user.

This Anti-Survivin Antibody is validated for use in WB, IP, IH for the detection of Survivin.

Physical form

Serum with no preservatives

Storage and Stability

Maintain at -20°C for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable