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Key Documents

8.53095

Sigma-Aldrich

Boc-D-Pro-OH

Novabiochem®

Synonym(s):

Boc-D-Pro-OH, N-α-t.-Boc-D-proline

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About This Item

Empirical Formula (Hill Notation):
C10H17NO4
CAS Number:
Molecular Weight:
215.25
MDL number:
UNSPSC Code:
12352209

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

>132 °C

application(s)

peptide synthesis

storage temp.

2-30°C

InChI

1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)

InChI key

ZQEBQGAAWMOMAI-UHFFFAOYSA-N

General description

Standard building block for introduction of D-proline amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Linkage

Replaces: 04-13-0027

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=2 in AcOH): +56.5 - +63.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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