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Key Documents

8.41705

Sigma-Aldrich

3-Mercapto-1,2-propanediol

for synthesis

Synonym(s):

3-Mercapto-1,2-propanediol, 1-Thioglycerol

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About This Item

Empirical Formula (Hill Notation):
C3H8O2S
CAS Number:
96-27-5
Molecular Weight:
108.16
MDL number:
MFCD00004879
UNSPSC Code:
12352104
EC Index Number:
202-495-0
NACRES:
NA.22

vapor pressure

<1 hPa ( 20 °C)

Quality Level

200

form

liquid

pH

4.79 (20 °C, 10 g/L in H2O)

mp

<-20 °C

transition temp

flash point 99 °C

solubility

slightly soluble >1000 g/L

density

1.247 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

InChI key

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

Application

  • Polyhydroxyurethanes and Semi-IPN Hydrogels: 3-Mercapto-1,2-propanediol is utilized in the simultaneous formation of polyhydroxyurethanes and multicomponent semi-interpenetrating polymer networks (semi-IPN) hydrogels, enhancing material properties for diverse biomedical applications (Carbajo-Gordillo et al., 2024).
  • Nanoparticle Functionalization: This compound facilitates the direct binding and characterization of enzymes onto iron oxide nanoparticles, showcasing its role in nanotechnology for biotechnological applications (Sidhu et al., 2024).
  • Shape Memory Polyurethanes: Used in the synthesis of multifunctional polyols via a facile thiol-ene click reaction method (Lee and Kim, 2023).
  • Low-Temperature Nanophosphor Synthesis: It is instrumental in the novel low-temperature synthesis of europium-doped yttrium oxide nanophosphors, utilized in near-UV light-emitting diodes, highlighting its critical role in advanced material manufacturing (Patwardhan et al., 2023).
  • Phosphorylcholine monomer: 3-Mercapto-1,2-propanediol is used in the synthesis of functional phosphorylcholine monomer of 2-((3-((2,3-dihydroxypropyl)thio)-2-methylpropanoyl)oxy)ethyl phosphorylcholine (PC-diol)via a click reaction (Hao et al., 2023).

Analysis Note

Assay (iodometric): ≥ 98.0 %
Identity (IR): passes test

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

210.2 °F - closed cup

Flash Point(C)

99 °C - closed cup

Certificates of Analysis (COA)

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