528822
PARP Inhibitor XII
The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
Synonym(s):
PARP Inhibitor XII, 3-(4-Chlorophenyl)quinoxaline-5-carboxamide
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C15H10ClN3O
CAS Number:
Molecular Weight:
283.71
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
light brown
solubility
DMSO: 10 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
A potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.
Packaging
Packaged under inert gas
Warning
Toxicity: Irritant (B)
Other Notes
Ishida, J., et al. 2006. Bioorg. Med. Chem.14, 1378.
Iwashita, A., et al. 2005. FEBS Lett.579, 1389.
Iwashita, A., et al. 2005. FEBS Lett.579, 1389.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service