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858141P

Avanti

17:1 Lyso PS

1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-[phospho-L-serine] (sodium salt), powder

Synonym(s):

110724

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About This Item

Empirical Formula (Hill Notation):
C23H43NNaO9P
CAS Number:
Molecular Weight:
531.55
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

form

powder

packaging

pkg of 1 × 100 mg (858141P-100mg)
pkg of 1 × 5 mg (858141P-5mg)

manufacturer/tradename

Avanti Polar Lipids 858141P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[Na+]

Application

17:1 Lyso PS may be used as a standard in graphitized carbon black-solid phase extraction (GCB-SPE) method for lipid extraction. It may also be used as an internal standard in the metabolomic analysis of cell and brain samples.

Biochem/physiol Actions

17:1 Lyso PS may act as an odd-chained LIPIDOMIX®quantitative mass spectrometry internal standard.

Packaging

5 mL Clear Glass Sealed Ampule (858141P-100mg)
5 mL Clear Glass Sealed Ampule (858141P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Daisuke Ogasawara et al.
Nature chemical biology, 14(12), 1099-1108 (2018-11-14)
ABHD12 metabolizes bioactive lysophospholipids, including lysophosphatidylserine (lyso-PS). Deleterious mutations in human ABHD12 cause the neurological disease PHARC, and ABHD12-/- mice display PHARC-like phenotypes, including hearing loss, along with elevated brain lyso-PS and features of stimulated innate immune cell function. Here
Biyu Hou et al.
Life sciences, 245, 117352-117352 (2020-02-02)
The depot-specific differences in lipidome of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) reflect heterogeneity of white adipose tissue (WAT), which plays a central role in its distinct response to outside stimuli. However, the detailed lipidome of depot-specific
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

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