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Key Documents

W222305

Sigma-Aldrich

Tributyrin

97%, FG

Synonym(s):

Glyceryl tributyrate, 1,2,3-Tributyrylglycerol, Glycerol tributyrate, Tributyrin

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About This Item

Linear Formula:
(CH3CH2CH2COOCH2)2CHOCOCH2CH2CH3
CAS Number:
Molecular Weight:
302.36
FEMA Number:
2223
Beilstein:
1714746
EC Number:
Council of Europe no.:
747
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.211
NACRES:
NA.21

biological source

synthetic

grade

FG
Halal

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 184.1903

Assay

97%

refractive index

n20/D 1.435 (lit.)

bp

129-131 °C/0.03 mmHg (lit.)
287-288 °C (lit.)

density

1.032 g/mL at 20 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

creamy; fatty; cheesy; waxy

SMILES string

CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC

InChI

1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3

InChI key

UYXTWWCETRIEDR-UHFFFAOYSA-N

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General description

Tributyrin is a short-chain triacylglycerol that mainly occurs in butter. It shows potent anti-cancer property.

Biochem/physiol Actions

Taste at 30 ppm

related product

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

345.2 °F - closed cup

Flash Point(C)

174 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy.
Chen ZX & Breitman TR
Cancer Research, 54(13), 3494-3499 (1994)
Emulsion-based delivery systems for tributyrin, a potential colon cancer preventative agent.
Li Y, et al.
Journal of Agricultural and Food Chemistry, 57(19), 9243-9249 (2009)
Renata de A B Assis et al.
Scientific reports, 7(1), 16133-16133 (2017-11-25)
The Xanthomonadaceae family consists of species of non-pathogenic and pathogenic γ-proteobacteria that infect different hosts, including humans and plants. In this study, we performed a comparative analysis using 69 fully sequenced genomes belonging to this family, with a focus on
Do-Won Jeong et al.
Food microbiology, 62, 92-98 (2016-11-28)
We assessed the safety of 49 Tetragenococcus halophilus strains isolated from doenjang in Korea. Minimum inhibitory concentration assays showed that all strains can be considered as susceptible to ampicillin, erythromycin, penicillin G, tetracycline, and vancomycin, but resistant to ciprofloxacin based
Tania Diaz-Vidal et al.
Biotechnology progress, 35(4), e2807-e2807 (2019-03-19)
Despite the proven therapeutic role of capsaicin in human health, its usage is still hampered by its high pungency. In this sense, nonpungent capsaicin analogues as olvanil are a feasible alternative to the unpleasant sensations produced by capsaicin while maintaining

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