D167800
2,3-Dimethylmaleic anhydride
98%
Synonym(s):
Dimethylmaleic anhydride
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About This Item
Empirical Formula (Hill Notation):
C6H6O3
CAS Number:
Molecular Weight:
126.11
Beilstein:
112044
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Assay
98%
form
flakes
bp
223 °C (lit.)
mp
93-96 °C (lit.)
SMILES string
CC1=C(C)C(=O)OC1=O
InChI
1S/C6H6O3/c1-3-4(2)6(8)9-5(3)7/h1-2H3
InChI key
MFGALGYVFGDXIX-UHFFFAOYSA-N
Application
Reagent used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Enhanced activity of immobilized dimethylmaleic anhydride-protected poly- and monoclonal antibodies.
E Hadas et al.
Journal of chromatography, 510, 303-309 (1990-06-27)
The effect of reversible protection of the free amino groups of poly- and monoclonal antibodies by dimethylmaleic anhydride on their binding activity following immobilization onto various carriers was studied. The treatment with dimethylmaleic anhydride resulted in a 1.6-1.8-fold increase in
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M Gerl et al.
Biochemistry, 27(11), 4089-4096 (1988-05-31)
Apoferritin from horse spleen is composed of 24 subunits that undergo partial dissociation after chemical modification with 2,3-dimethylmaleic anhydride (DMMA), yielding dimeric, trimeric, and tetrameric intermediates, stable at pH 8.5 and 0 degrees C. Deacylation at neutral pH and elevated
Bo Reum Lee et al.
International journal of pharmaceutics, 392(1-2), 78-82 (2010-03-20)
A novel synthetic nanocomplex was constructed from glycol chitosan (GCS) grafted with 2,3-dimethylmaleic anhydride (DMA) (denoted as 'GCD' hereafter) and lysozyme (isoelectric point=10.9) as a model protein. This is a core-shell supramolecular assemble formed through electrostatic interactions between anionic GCD
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