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802158

Sigma-Aldrich

Polycaprolactone dimethacrylate

average Mn 3,000

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About This Item

Linear Formula:
(C6H10O2)nC12H18O5
UNSPSC Code:
12162002

form

powder

mol wt

average Mn 3,000

mp

38-43 °C

storage temp.

−20°C

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Application

Polycaprolactone is a biodegradable polymer commonly used in biomedical applications. A light-activated Polycaprolactone dimethacrylate gel was used for the sustained delivery of an anti-VEGF antibody.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Puneet Tyagi et al.
Molecular pharmaceutics, 10(8), 2858-2867 (2013-06-06)
A light-activated polycaprolactone dimethacrylate (PCM) and hydroxyethyl methacrylate (HEMA) based gel network was developed to sustain the release of stable, active bevacizumab (an anti-VEGF antibody used to treat choroidal neovascularization) and used to assess sustained ex vivo delivery in rabbit

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We will explore the technological advances that have contributed toward the progress of 3DP of tissue engineering scaffolds, current materials used to create 3DP scaffolds, and the challenges that remain.

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

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