752800

[(S,S)-Teth-TsDpen RuCl]

• Synonym(s): stereoisomer of Chloro[N-[(1S,2S)-1,2-diphenyl-2-[(R)-[3-(η6-phenyl)propyl]amino-κN]ethyl]-4-methylbenzenesulfonamidato-κN]ruthenium
• Empirical Formula (Hill Notation): C₃₀H₃₁ClN₂O₂RuS
• CAS Number: 851051-43-9
• Molecular Weight: 620.17
• MDL number: MFCD16294984
• UNSPSC Code: 12352103
• PubChem Substance ID: 329766311
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• optical activity: [α]22/D +339°, c = 0.5% in chloroform
• reaction suitability: core: ruthenium; reagent type: catalyst
• mp: 260-268 °C
• storage temp.: 2-8°C
• SMILES string: Cc1ccc(cc1)S(=O)(=O)N2[C@H]([C@@H]([N@@H](CCCc3ccccc3)[Ru]2Cl)c4ccccc4)c5ccccc5
• InChI: 1S/C30H31N2O2S.ClH.Ru/c1-24-19-21-28(22-20-24)35(33,34)32-30(27-17-9-4-10-18-27)29(26-15-7-3-8-16-26)31-23-11-14-25-12-5-2-6-13-25;;/h2-10,12-13,15-22,29-31H,11,14,23H2,1H3;1H;/q-1;;+2/p-1/t29-,30-;;/m0../s1
• InChI key: MDABGVLQRDDWLY-ARDORAJISA-M

Description

Application

[(S,S)-Teth-TsDpen RuCl] is a catalyst for the asymmetric hydrogenation of ketones. It can be used as a catalyst:

• In the reduction of a ketone intermediate for the synthesis of esketamine.
• In asymmetric hydrogenation of acetylenic ketones.
• For the preparation of (3S,6S)-1,8-diphenylocta-1,7-diyne-3,6-diol starting from 1,8-diphenylocta-1,7-diyne-3,6-dione.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable