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Sigma-Aldrich

PAMAM Dendrimer Kit, generations 0-3

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About This Item

UNSPSC Code:
12162002
eCl@ss:
32161000
NACRES:
NA.23

description

amino surface groups

feature

core type ethylenediamine core (2-carbon core)

storage temp.

2-8°C

General description

PAMAM Dendrimer Kit, generations 0-3 consists of a class of hyper-branched polymers with an ethylene diamine core, and amido amine as a branching structure that facilitates the formation of amine terminated full generation or carboxyl-terminated half generation dendrimers. It can be used in the functionalization of polymer with drugs, nucleic acids and imaging systems.

Packaging

unit weight includes solvent

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

Kit Components Also Available Separately

Product No.
Description
SDS
  • 412368PAMAM dendrimer, ethylenediamine core, generation 0.0 solution, 20 wt. % in methanol 1 gSDS
  • 412384PAMAM dendrimer, ethylenediamine core, generation 1.0 solution, 20 wt. % in methanol 1 gSDS
  • 412406PAMAM dendrimer, ethylenediamine core, generation 2.0 solution, 20 wt. % in methanol 1 gSDS
  • 412422PAMAM dendrimer, ethylenediamine core, generation 3.0 solution, 20 wt. % in methanol 1 gSDS

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3

Target Organs

Eyes,Central nervous system, Respiratory system

Storage Class Code

3 - Flammable liquids

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

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Polyamidoamine (PAMAM) dendrimers as biocompatible carriers of quinolone antimicrobials: an in vitro study
Cheng Y, et al.
European Journal of Medicinal Chemistry, 42(7), 1032-1038 (2007)
Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: a potential oral delivery system?
Wiwattanapatapee R, et al.
Pharmaceutical Research, 17(8), 991-998 (2000)
Anti-angiogenesis effect of generation 4 polyamidoamine/vascular endothelial growth factor antisense oligodeoxynucleotide on breast cancer in vitro
Gu S, et al.
Journal of Zhejiang University. Science, 10(3), 159-167 (2009)
Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery
Sadekar S and Ghandehari H
Advanced Drug Delivery Reviews, 64(6), 571-588 (2012)

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