633003

5-Chlorothiophene-2-carboxylic acid

97%

• Empirical Formula (Hill Notation): C₅H₃ClO₂S
• CAS Number: 24065-33-6
• Molecular Weight: 162.59
• MDL number: MFCD00041426
• UNSPSC Code: 12352100
• PubChem Substance ID: 24882532
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• mp: 154-158 °C (lit.)
• functional group: carboxylic acid; chloro
• SMILES string: OC(=O)c1ccc(Cl)s1
• InChI: 1S/C5H3ClO2S/c6-4-2-1-3(9-4)5(7)8/h1-2H,(H,7,8)
• InChI key: QZLSBOVWPHXCLT-UHFFFAOYSA-N

Description

Application

5-Chlorothiophene-2-carboxylic acid can be used in the synthesis of the following:

• rivaroxaban, an oxazolidinone derivative used in the treatment of thromboembolic disorders
• 5-chloro-4-nitrothiophene-2-carboxylic acid, which can be used in the synthesis of thieno[2,3-b][1,4]thiapezine-5-ones

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H318
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves