62562

Lithium methoxide solution

~10% in methanol (T, ~2.2 M)

• Synonym(s): Lithium methylate
• Linear Formula: CH₃OLi
• CAS Number: 865-34-9
• Molecular Weight: 37.97
• Beilstein: 3552389
• MDL number: MFCD00036357
• UNSPSC Code: 12352300
• PubChem Substance ID: 57651898
• NACRES: NA.22

Properties

• concentration: ~10% in methanol (T, ~2.2 M)
• density: 0.85 g/mL at 20 °C
• SMILES string: [Li+].C[O-]
• InChI: 1S/CH3O.Li/c1-2;/h1H3;/q-1;+1
• InChI key: JILPJDVXYVTZDQ-UHFFFAOYSA-N

Description

General description

Lithium methoxide solution is a useful reagent in organic synthesis with a range of applications. For example, it is used as a strong base in deprotonation reactions of various acidic functional groups, such as alcohols, phenols, and carboxylic acids. It also acts as a catalyst in esterification reactions. It can catalyze the reaction of carboxylic acids with alcohols to form esters.

Application

Lithium methoxide solution (10% in methanol) can be used as a source of lithium ions in the synthesis of dilithium (2,3-dilithium-oxy)-terephthalate, which is studied for its electrochemical behavior.

Safety Information

• Pictograms: GHS02,GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H251,H301 + H311 + H331,H314,H370
• Precautionary Statements: P210 - P235 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Self-heat. 1 - Skin Corr. 1B - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 2
• Flash Point(F): 53.6 °F
• Flash Point(C): 12 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves