450243
Sodium orthovanadate
99.98% trace metals basis
Synonym(s):
Trisodium vanadate
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About This Item
Linear Formula:
Na3VO4
CAS Number:
Molecular Weight:
183.91
EC Number:
MDL number:
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22
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Assay
99.98% trace metals basis
form
solid
reaction suitability
core: vanadium
reagent type: catalyst
mp
850-866 °C (lit.)
SMILES string
[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O
InChI
1S/3Na.4O.V/q3*+1;;3*-1;
InChI key
IHIXIJGXTJIKRB-UHFFFAOYSA-N
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Application
Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
- Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
- Nanorods of vanadium oxide particles by glycothermal method.
- Yttrium vanadate (YVO4) doped with colloidal europium.
Biochem/physiol Actions
An inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.
Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.
Packaging
Exhibits various biological and physiological effects in the human body
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A Morita et al.
Cell death and differentiation, 13(3), 499-511 (2005-09-03)
We previously reported that p42/SETbeta is a substrate for caspase-7 in irradiated MOLT-4 cells, and that treating the cells with sodium orthovanadate (vanadate) inhibits p42/SETbeta's caspase-mediated cleavage. Here, we initially found that the inhibitory effect of vanadate was due to
Synthesis and characterizations of YVO4: Eu colloids.
Huignard A, et al.
Chemistry of Materials, 14(5), 2264-2269 (2002)
Glycothermal synthesis of assembled vanadium oxide nanostructures for gas sensing.
Fu H, et al.
Journal of Nanoparticle Research, 14(6), 871-871 (2012)
Yu Hasegawa et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 875-881 (2006-02-08)
Vanadium is widely distributed in the environment and exhibits various biological and physiological effects in the human body. We previously documented the neuroprotective effect of sodium orthovanadate (SOV) against in rodents i.v. injected with 2 ml/kg 50 mM SOV just
Synthesis and characterization of TM-MCM-48 (TM= Mn, V, Cr) and their catalytic activity in the oxidation of styrene.
Gomez S, et al.
J. Catal., 233(1), 60-67 (2005)
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