429066

(3-Bromopropoxy)-tert-butyldimethylsilane

97%

• Synonym(s): (3-Bromopropoxy)(1,1-dimethylethyl)dimethylsilane, 1-((tert-Butyldimethylsilyl)oxy)-3-bromopropane, 1-Bromo-3-(tert-butyldimethylsiloxy)propane, 1-Bromo-3-[(tert-butyldimethylsilanyl)oxy]propane, 1-Bromo-3-[(tert-butyldimethylsilyl)oxy]propane, 3-((tert-Butyldimethylsilyl)oxy)-1-bromopropane
• Linear Formula: Br(CH₂)₃OSi(CH₃)₂C(CH₃)₃
• CAS Number: 89031-84-5
• Molecular Weight: 253.25
• MDL number: MFCD00216589
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866833
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: liquid
• contains: sodium carbonate as stabilizer
• refractive index: n20/D 1.451 (lit.)
• bp: 182 °C (lit.)
• density: 1.093 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)[Si](C)(C)OCCCBr
• InChI: 1S/C9H21BrOSi/c1-9(2,3)12(4,5)11-8-6-7-10/h6-8H2,1-5H3
• InChI key: QGMROEZDWJTIDW-UHFFFAOYSA-N

Description

General description

(3-Bromopropoxy)-tert-butyldimethylsilane is a bromo silyl ether.

Application

(3-Bromopropoxy)-tert-butyldimethylsilane may be used to introduce propanol functionality to many pharmaceuticals.
It may be used as an alkylating agent in the synthesis of the following:

• N-[2-[N-[3-(tert-butyldimethylsilyloxy)propyl]-N-ethylamino]ethyl]phthalimide
• O-(3-tert-butyldimethylsilyloxypropyl)-N-(tert-butoxycarbonyl)-L-tyrosine methyl ester
• tert-butyldimethyl-[3-(3-methyl-2-nitrophenoxy)propoxy]silane

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 185.0 °F - closed cup
• Flash Point(C): 85 °C - closed cup