408484

Boc-Arg-OH

for peptide synthesis

• Synonym(s): N_α-(tert-Butoxycarbonyl)-L-arginine, N_α-Boc-L-arginine
• Linear Formula: HN=C(NH₂)NH(CH₂)₃CH(COOH)NHC(O)OC(CH₃)₃
• CAS Number: 13726-76-6
• Molecular Weight: 274.32
• Beilstein: 2419628
• EC Number: 237-295-2
• MDL number: MFCD00042632
• UNSPSC Code: 12352209
• PubChem Substance ID: 24865572
• NACRES: NA.22

Properties

• product name: Boc-Arg-OH,
• form: powder
• optical activity: [α]20/D −6.5°, c = 1 in acetic acid
• reaction suitability: reaction type: Boc solid-phase peptide synthesis
• impurities: 5-10% n-butanol
• application(s): peptide synthesis
• SMILES string: CC(C)(C)OC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C11H22N4O4/c1-11(2,3)19-10(18)15-7(8(16)17)5-4-6-14-9(12)13/h7H,4-6H2,1-3H3,(H,15,18)(H,16,17)(H4,12,13,14)/t7-/m0/s1
• InChI key: HSQIYOPBCOPMSS-ZETCQYMHSA-N

Description

Application

• Studying the kinetics of tanning reactions: The study compares the color development kinetics in tanning reactions involving dihydroxyacetone with both free and Boc-protected basic amino acids, highlighting Boc-Arg-OH′s role in stabilizing reactive intermediates in cosmetic chemistry (Sun et al., 2022).
• Protonation states in peptide synthesis: This research examines the side-chain protonation states of a fluorescent arginine derivative, including Boc-Arg-OH, to optimize fluorescence in peptide synthesis for bioimaging applications (Marshall et al., 2019).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves